CHEM601 - Chemical Information

Status
O
Activity
LEC
Section number integer
2
Title (text only)
Chemical Information
Term
2020A
Subject area
CHEM
Section number only
002
Section ID
CHEM601002
Course number integer
601
Registration notes
Permission Needed From Department
Meeting times
F 10:30 AM-12:00 PM
Level
graduate
Instructors
Judith N. Currano
Description
This course examines the structure and organization of the chemical literature and introduces techniques of searching this literature, focusing on the logic and thought processes necessary for effective information retrieval. Each technique is illustrated using information tools available at the University of Pennsylvania, and we take an "under the hood" look at the organization and functionality of each tool introduced. Students should choose a course section based on their preferred area of chemistry research: organic, inorganic, biological, and physical chemistry; all four sections are taught at a level appropriate for graduate students and advanced undergraduates. Topics vary by section, but all students learn the basics of subject, author, structure, and reaction searching, and a unit on ethics in publication and scholarly communication completes the course.
Course number only
601
Use local description
No

CHEM764 - Materials Chemistry

Status
O
Activity
LEC
Section number integer
1
Title (text only)
Materials Chemistry
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM764001
Course number integer
764
Registration notes
Permission Needed From Department
Meeting times
TR 09:00 AM-10:30 AM
Level
graduate
Instructors
Christopher B. Murray
Description
This course will focus on the structure-property relationships in materials chemistry on length scales from atomic dimension up to the microscale and then core concepts to Chemical design that underpins future, "Energy and Environmental Sustainability." We will introduce the "12 Principles of Green Chemistry" and "12 Principles of Green Engineering" as a guide to modern materials chemistry design and then follow a trajectory that proceeds with increasing length scales of ordering in the solid state. We will introduce techniques of x-ray, neutron, electron, and ion beam based scattering, real space imaging and spectroscopies and use these to explore non-crystalline materials (amorphous, glasses, and time permitting quasicrystals and aperiodic systems) and crystalline solids. Studies will proceed from atomic scales through nanoscale, mesoscale, and micro-scale discussing the emergence of band structure and delcocalized electronic and optical properties that emerge due tothe finite scale of ordering and influence of the surface. We will then focus on how these foundations of materials chemistry are shaping advances in solar energy utilization with photochemistry and photoelectrochemistry and materials for photovoltaic and enabling advances electrochemical energy conversion and storage.
Course number only
764
Use local description
No

CHEM762 - X Ray I

Status
O
Activity
LEC
Section number integer
1
Title (text only)
X Ray I
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM762001
Course number integer
762
Registration notes
Permission Needed From Department
Meeting times
MW 09:00 AM-10:30 AM
Level
graduate
Instructors
Patrick J Carroll
Description
An introduction to the theory and practice of structure determination by X-ray crystallography. Topics discussed include point group and space group symmetry, structure factor theory, data collection methods and a survey of solution methods. The course culminates with a series of real-world structure determinations worked through in-class using the XSeed program package.
Course number only
762
Use local description
No

CHEM761 - Coordination Chemistry

Status
X
Activity
LEC
Section number integer
1
Title (text only)
Coordination Chemistry
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM761001
Course number integer
761
Registration notes
Permission Needed From Department
Meeting times
CANCELED
Level
graduate
Description
Ligands have a remarkable ability to alter the properties of metal ions, and the study of this coordination chemistry underlies many modern advances in science, including energy harvesting and storage, chemical catalysis, and sustainability. This course explores the relationships between the identities of ligands and the physical manifestations that result from their binding to metal centers. Topics to be covered include: symmetry and chirality in molecular complexes, variations in coordination number, ligand field effects, recent advanced in bonding theory, and inorganic reaction mechanisms.
Course number only
761
Use local description
No

CHEM751 - Chemical Biology

Status
O
Activity
LEC
Section number integer
401
Title (text only)
Chemical Biology
Term
2020A
Subject area
CHEM
Section number only
401
Section ID
CHEM751401
Course number integer
751
Registration notes
Permission Needed From Department
Meeting times
TR 09:00 AM-10:30 AM
Level
graduate
Instructors
Megan L Matthews
Ernest J Petersson
Description
This course focuses on current topics in Chemical Biology, particularly experiments in which 1) chemical synthesis enables one to probe or control biological systems, or 2) manipulation of biological systems facilitates novel chemical syntheses. The course is broadly divided into two sections, one dealing with the study of individual proteins and nucleic acids, and one dealing with complex cellular systems. As the goal of the course is to familiarize students with innovative recent experimental approaches and to stimulate them to conceive of their own new methodology, students will be responsible for delivering presentations on topics selected from the literature, designing experiments to address currently unsolved problems in Chemical Biology (in take-home examinations), and generating several novel research proposal ideas, one of which will be elaborated into a full proposal.
Course number only
751
Cross listings
BMB751401
Use local description
No

CHEM745 - Total Synthesis

Status
O
Activity
LEC
Section number integer
1
Title (text only)
Total Synthesis
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM745001
Course number integer
745
Registration notes
Permission Needed From Department
Meeting times
TR 03:00 PM-04:30 PM
Level
graduate
Instructors
Amos Brittain Smith
Description
The focus of this course comprise the development of two synthetic strategies to access architecturally complex natural products of biological significance exploiting innovative chemistry. Lectures towards this end are given. As a project, each studnet is given a different complex natural product and expected at the end of the course to deveop two strategies, one based on asymmetric induction to provide the absolute stereochemical structure, the second where the absolute stereochemistry derives from commercially available starting materials.
Course number only
745
Use local description
No

CHEM744 - Bioinspired Synthesis

Status
O
Activity
LEC
Section number integer
1
Title (text only)
Bioinspired Synthesis
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM744001
Course number integer
744
Registration notes
Permission Needed From Department
Meeting times
MW 10:30 AM-12:00 PM
Level
graduate
Description
This class will discuss selected topics related to Bioinspired synthesis, methods, tactics and strategies. Target molecules, methods and strategies are designed by using biological systems as models.
Course number only
744
Use local description
No

CHEM743 - Heterocyclic Chemistry

Status
X
Activity
LEC
Section number integer
1
Title (text only)
Heterocyclic Chemistry
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM743001
Course number integer
743
Registration notes
Permission Needed From Department
Meeting times
CANCELED
Level
graduate
Description
The course deals with topics in Heterocyclic Chemistry. It covers nitrogen-containing monocyclic hetero rings, examining the most recent syntheses, the reactions and their mechanisms. The course will focus on recent variations and improvements of known heterocycles as well as their synthetic utility. Students will be expected to read critically a recent article on heterocyclic chemistry and do a presentation to the class.
Course number only
743
Use local description
No

CHEM742 - Medicinal Chemistry

Status
O
Activity
LEC
Section number integer
1
Title (text only)
Medicinal Chemistry
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM742001
Course number integer
742
Registration notes
Permission Needed From Department
Meeting times
MF 10:30 AM-12:00 PM
Level
graduate
Instructors
Donna Huryn
Description
This course focuses on concepts and strategies in medicinal chemistry, and how it is applied to modern drug discovery and development. Topics include the drug discovery process, drug targets (GRCR?s, enzymes, channels etc.), physical chemistry of molecular interactions between drug and target, drug design, methods for hit and lead identification, lead optimization, chemical biology, natural products chemistry and combinatorial and diversity oriented synthesis. This course is geared to upper level undergraduate students in chemistry or biochemistry, and first year chemistry graduate students. A strong understanding of organic chemistry is required.
Course number only
742
Use local description
No

CHEM741 - Spectroscopy

Status
O
Activity
LEC
Section number integer
1
Title (text only)
Spectroscopy
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM741001
Course number integer
741
Registration notes
Permission Needed From Department
Meeting times
MW 09:00 AM-10:30 AM
Level
graduate
Instructors
Jun Gu
William P Dailey
Description
The course will cover Nuclear Magnetic Resonance (NMR) theory at a level appropriate for graduate students in Organic Chemistry. It will also provide hands-on practical training in the correct use of high-field NMR spectrometers. Organic Spectroscopic methods for the determination of structure using NMR will be stressed. Permission of instructor required.
Course number only
741
Use local description
No