CHEM751 - Chemical Biology

Activity
LEC
Section number integer
401
Title (text only)
Chemical Biology
Term
2020A
Subject area
CHEM
Section number only
401
Section ID
CHEM751401
Course number integer
751
Registration notes
Permission Needed From Department
Meeting times
TR 09:00 AM-10:30 AM
Meeting location
CHEM 119
Level
graduate
Instructors
Ernest J Petersson
Description
This course focuses on current topics in Chemical Biology, particularly experiments in which 1) chemical synthesis enables one to probe or control biological systems, or 2) manipulation of biological systems facilitates novel chemical syntheses. The course is broadly divided into two sections, one dealing with the study of individual proteins and nucleic acids, and one dealing with complex cellular systems. As the goal of the course is to familiarize students with innovative recent experimental approaches and to stimulate them to conceive of their own new methodology, students will be responsible for delivering presentations on topics selected from the literature, designing experiments to address currently unsolved problems in Chemical Biology (in take-home examinations), and generating several novel research proposal ideas, one of which will be elaborated into a full proposal.
Course number only
751
Cross listings
BMB751401
Use local description
No

CHEM745 - Total Synthesis

Activity
LEC
Section number integer
1
Title (text only)
Total Synthesis
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM745001
Course number integer
745
Registration notes
Permission Needed From Department
Meeting times
TR 03:00 PM-04:30 PM
Meeting location
CHEM 119
Level
graduate
Instructors
Amos Brittain Smith
Description
The focus of this course comprise the development of two synthetic strategies to access architecturally complex natural products of biological significance exploiting innovative chemistry. Lectures towards this end are given. As a project, each studnet is given a different complex natural product and expected at the end of the course to deveop two strategies, one based on asymmetric induction to provide the absolute stereochemical structure, the second where the absolute stereochemistry derives from commercially available starting materials.
Course number only
745
Use local description
No

CHEM744 - Bioinspired Synthesis

Activity
LEC
Section number integer
1
Title (text only)
Bioinspired Synthesis
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM744001
Course number integer
744
Registration notes
Permission Needed From Department
Meeting times
MW 10:30 AM-12:00 PM
Meeting location
CHEM 514
Level
graduate
Description
This class will discuss selected topics related to Bioinspired synthesis, methods, tactics and strategies. Target molecules, methods and strategies are designed by using biological systems as models.
Course number only
744
Use local description
No

CHEM743 - Heterocyclic Chemistry

Activity
LEC
Section number integer
1
Title (text only)
Heterocyclic Chemistry
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM743001
Course number integer
743
Registration notes
Permission Needed From Department
Meeting times
MW 10:30 AM-12:00 PM
Level
graduate
Description
The course deals with topics in Heterocyclic Chemistry. It covers nitrogen-containing monocyclic hetero rings, examining the most recent syntheses, the reactions and their mechanisms. The course will focus on recent variations and improvements of known heterocycles as well as their synthetic utility. Students will be expected to read critically a recent article on heterocyclic chemistry and do a presentation to the class.
Course number only
743
Use local description
No

CHEM742 - Medicinal Chemistry

Activity
LEC
Section number integer
1
Title (text only)
Medicinal Chemistry
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM742001
Course number integer
742
Registration notes
Permission Needed From Department
Meeting times
MF 10:30 AM-12:00 PM
Meeting location
VAGL 4000
Level
graduate
Instructors
Donna Huryn
Description
This course focuses on concepts and strategies in medicinal chemistry, and how it is applied to modern drug discovery and development. Topics include the drug discovery process, drug targets (GRCR?s, enzymes, channels etc.), physical chemistry of molecular interactions between drug and target, drug design, methods for hit and lead identification, lead optimization, chemical biology, natural products chemistry and combinatorial and diversity oriented synthesis. This course is geared to upper level undergraduate students in chemistry or biochemistry, and first year chemistry graduate students. A strong understanding of organic chemistry is required.
Course number only
742
Use local description
No

CHEM741 - Spectroscopy

Activity
LEC
Section number integer
1
Title (text only)
Spectroscopy
Term session
2
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM741001
Course number integer
741
Registration notes
Permission Needed From Department
Meeting times
MW 09:00 AM-10:30 AM
Meeting location
CHEM 119
Level
graduate
Instructors
Jun Gu
William P Dailey
Description
The course will cover Nuclear Magnetic Resonance (NMR) theory at a level appropriate for graduate students in Organic Chemistry. It will also provide hands-on practical training in the correct use of high-field NMR spectrometers. Organic Spectroscopic methods for the determination of structure using NMR will be stressed. Permission of instructor required.
Course number only
741
Use local description
No

CHEM723 - Dynamics of Polymers

Activity
LEC
Section number integer
1
Title (text only)
Dynamics of Polymers
Term session
1
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM723001
Course number integer
723
Registration notes
Permission Needed From Department
Meeting times
MW 10:30 AM-12:00 PM
Level
graduate
Instructors
Zahra Fakhraai
Description
This course discussed the structure of polymers from a statistical physics point of view as well as dynamical response of polymeric systems such as mechanical response of polymer melts, polymer glass transition, properties of polymers in solutions, and properties of block co-polymers and ionomers.
Course number only
723
Use local description
No

CHEM708 - Topics in Photochemistry

Activity
LEC
Section number integer
1
Title (text only)
Topics in Photochemistry
Term
2020A
Subject area
CHEM
Section number only
001
Section ID
CHEM708001
Course number integer
708
Registration notes
Permission Needed From Department
Meeting times
TR 01:30 PM-03:00 PM
Meeting location
CHEM 119
Level
graduate
Instructors
Eric J Schelter
David M Chenoweth
Description
This course, for graduate students, encompasses topics in fundamental and applied photochemistry and photophysics from the fields of organic and inorganic chemistry. Key topics and concepts will include basic electronic structure, interactions of light with matter/electronic transitions, UV-Vis absorption and emission spectroscopy, energy transfer, kinetics/dynamics, Jablonski diagrams, electron transfer, and chemical reactivity. These topics and concepts will be covered in the context of frontier applications including OLEDs, photoredox catalysis, energy conversion, solar fuels, and artificial photosynthesis, organic photosynthesis, molecular imaging, and optogenetic tools among others.
Course number only
708
Use local description
No

CHEM601 - Chemical Information

Activity
LEC
Section number integer
3
Title (text only)
Chemical Information
Term
2020A
Subject area
CHEM
Section number only
003
Section ID
CHEM601003
Course number integer
601
Registration notes
Permission Needed From Department
Meeting times
F 09:00 AM-10:30 AM
Level
graduate
Instructors
Judith N. Currano
Description
This course examines the structure and organization of the chemical literature and introduces techniques of searching this literature, focusing on the logic and thought processes necessary for effective information retrieval. Each technique is illustrated using information tools available at the University of Pennsylvania, and we take an "under the hood" look at the organization and functionality of each tool introduced. Students should choose a course section based on their preferred area of chemistry research: organic, inorganic, biological, and physical chemistry; all four sections are taught at a level appropriate for graduate students and advanced undergraduates. Topics vary by section, but all students learn the basics of subject, author, structure, and reaction searching, and a unit on ethics in publication and scholarly communication completes the course.
Course number only
601
Use local description
No

CHEM567 - Bio-Inorganic Chemistry

Activity
LEC
Section number integer
401
Title (text only)
Bio-Inorganic Chemistry
Term
2020A
Syllabus URL
Subject area
CHEM
Section number only
401
Section ID
CHEM567401
Course number integer
567
Registration notes
Permission Needed From Department
Meeting times
MW 10:30 AM-12:00 PM
Meeting location
CHEM B13
Level
graduate
Instructors
Ivan J. Dmochowski
Description
The course covers selected topics in bioinorganic chemistry; special emphasis is placed on dioxygen chemistry and electron transfer processes. Course topics include: (i) oxygen uptake and utilization; (ii) diatomic oxygen trans port; (iii) diatomic and monoatomic oxygen incorporation into substrates; (iv) metalloenzyme-catalyzed C-C bond formation; (v) the metallobiochemistry of DNA; (vi) metal-sulfide proteins; (vii) manganese-containing metalloproteins; (viii) Photosystem II: light-driven electron transfer and the biological water-splitting reaction; (ix) biological electron transfer; (x) electron transfer theory; (xi) mechanisms of energy storage and release; and (xii) long-distance electron transfer reactions.
Course number only
567
Cross listings
BMB567401
Use local description
No