This course encompasses a comprehensive survey of the chemistry and properties of the p-block elements of the periodic table. Topics include syntheses, structures and reactivities of important compounds. In addition, alternative bonding theories which have been used to explain the unique properties of thesecompounds are critically examined.

Basic concepts and principles of chemistry and their applications in chemistry and closely-related fields. The first term emphasizes the understanding of chemical reactions through atomic and molecular structure. This is a university level course, treating the material in sufficient depth so that students can solve chemical problems and can understand the principles involved in their solution. It includes an introduction to condensed matter. This course is suitable for majors or non-majors and is recommended to satisfy either major or pre-professional requirements for general chemistry. This course is presented for students with high school chemistry and calculus. Students with a lesser background than this should take CHEM 1011. Prerequisite: Students with credit for CHEM 1011 may not enroll in CHEM 1012. Credit is not awarded for both CHEM 1011 and CHEM 1012.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

Fundamentals of biological chemistry, including the structure of biological macromolecules and their mechanism of action, intermediary metabolism, and the chemical basis of information transfer. Course can be taken concurrently with CHEM 2420 or CHEM 2425.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

CHEM 1011 is an introductory college-level course in chemistry intended for students with less preparation in high school chemistry and mathematics. The course content parallels that of CHEM 1012, but with emphasis placed on developing problem-solving strategies and developing the underlying chemical principles. The course will take an 'atoms first' approach to introductory chemistry, where topical coverage includes an overview of quantum theory, atomic structure, the periodic table, chemical bonding, elementary chemical reactions, stoichiometry, ideal gases, and intermolecular interactions. Topics from mathematics and physics that are necessary to chemical problem-solving will be included as needed. Prerequisite: Students with credit for CHEM 1012 may not enroll in CHEM 1011. Credit will not be awarded for both CHEM 1011 and 1012.

Natural products, such as tetrodotoxin, kainic acid and morphine, have played a crucial role in the development of neuroscience. Using selected chemical syntheses as a framework, I will provide an introduction to neuroscience for chemists blended with an intense course in synthetic design ("Syntheseplanung"). The structure, function and synthesis of the following molecules will be analyzed: tetrodotoxin, saxitoxin, kainic acid, nicotine, epibatidine, coniine, tubocurarine, histrionicotoxin, ibotenic acid, strychnine, picrotine, chrysanthemic acid, ivermectin, muscarine, morphine, salvinorin A, THC, lysergic acid, forskolin, staurosporin, eglumegad, physostigmine, huperzin A, galanthamine, cocaine, reserpine, thapsigargin, ouabagenin, ryanodine, capsaicin, resiniferatoxin, retinal, carotene, menthol, santalol, camphor, and the prostaglandins. The structure and function of important ion channels, GPCRs, transporters and enzymes and their ligands will be discussed using PyMol files.
The goal of this course is to get as many synthetic chemists excited about neuroscience as possible (and a few neuroscientists stoked about synthesis). The importance of structural and pharmacological databases (PDB and IUPHAR, respectively) and the usefulness of the Reaxys database (and SciFinder) for synthetic planning will be demonstrated.
Requirements: A familiarity with synthetic organic chemistry and (named) chemical reactions, a mastery of the Nernst equation, and a willingness to learn more about one of the greatest, if not the greatest scientific challenges of our times: to figure out how the human brain work