Organic Chemistry Seminar: Dr. Andrew McNally, Colorado State University

November 12, 2018 - 12:00 PM - 01:00 PM
Speaker: 

Dr. Andrew McNally

Title: Selective Functionalization of Pyridines, Diazine and Pharmaceuticals via Heterocyclic Phosphonium Salts
Abstract: Selective methods that can functionalize electron-deficient heterocycles are in great demand due to their prevalence in biologically active compounds. Pyridines and diazines, in particular, are widespread components of pharmaceutical compounds yet methods to transform these motifs into valuable derivatives are still greatly sought after. We will present a selection of catalytic and non-catalytic methods using  phosphorus intermediates that enable multiple new bond-constructions on these heterocycles. A particular emphasis will be placed on phosphorus ligand-coupling reactions that represent an alternative means to form C–C and C-Heteroatom bonds.
Location: 

Carol Lynch Lecture Hall

Chemistry Complex

Attached Document: 

Host: Dr. Walsh

inquires rvargas@sas.upenn.edu

Department of Chemistry

231 S. 34 Street, Philadelphia, PA 19104-6323

215.898.8317 voice | 215.573.2112 fax | web@chem.upenn.edu