William P. Dailey

Associate Professor of Chemistry
Organic Chemistry

Office: 551 N
Lab: 512 N
Phone: (215) 898-2704
Email: daileysasupennedu

Jump to: Research Statement | Education and Academic History | Selected Publications

Research Statement
Our research group is interested in the areas of reactive intermediates, fluorine substituent effects, novel strained-ring compounds including strained-ring nitro compounds, mechanistic chemistry, matrix-isolation chemistry, and computational chemistry. We incorporate ab initio molecular orbital calculations as well as synthesis and mechanistic studies into the majority of our projects.

Current interests include the synthesis and reactions of fluorinated cumulenones, generation, reactions and direct spectroscopic observation of carbenes and other reactive compounds under matrix isolation conditions, synthesis of strained caged-ring compounds, and the preparation of new fluorinated materials.

Education and Academic History

Selected Publications
T. Martinu and W.P. Dailey " Facile One-Pot Preparation of 3-Chloro-2-(chloromethyl)propene and an Ab Initio Study of the Deamination Reaction of Nitrosoaziridine", J. Org. Chem. 2000, 65(20); 6784-6786.

T. Hirayama et al. "Responsive-to-Antagonist, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis", Cell 1999, 97, 383-393.

T.D. Golobish et al. " Preparation of 9,9-Dimethoxytetracyclo[8.5.0.02,8.07,11]pentadeca-3,5,12,14,-tetraene and Conversion to Hexacyclo[8.5.1.14,7.05,14.06,12.011,15.016,17]heptadeca-2,8-diene-13-one using a Domino Diels-Alder Reaction" , Tetrahedron 1998, 54, 7013 - 7024.

D. L. S. Brahms and W. P. Dailey "Fluorinated Carbenes", Chem. Rev. 1996, 96, 1585-1632.

T. D. Golobish and W. P. Dailey "Synthesis and Structure of Bishomohexaprismanedione", Tetrahedron Lett. 1996, 37, 3239 - 3242.

D. L. S. Yokotsuji et al. "Generation, Direct Observation under Matrix-isolation Conditions and Ab Initio Calculations for 2-Azacyclopenta-2, 4-dien-1-one", J. Phys. Chem. 1995, 99, 15870 - 15873 .

K. M. Lynch and W. P. Dailey "Improved Preparations of 3-Chloro-2-(chloromethyl)-1-propene and 1,1-Dibromo-2,2-bis(chloromethyl)cyclopropane: Intermediates in the Synthesis of [1.1.1]Propellane", J. Org. Chem. 1995, 60, 4666 - 4668.

C. A. Jacobs, J. C. Brahms, W. P. Dailey, K. Beran and M. D. Harmony "Synthesis, Microwave Spectrum, and Ab Initio Calculations for Difluorocyclopropenone", J. Am. Chem. Soc. 1992, 114, 115-121.

M. A. Forman and W. P. Dailey "The Lithium Perchlorate-Diethyl Ether Rate Acceleration of the Diels-Alder Reaction: Lewis Acid Catalysis by Lithium Ion", J. Am. Chem. Soc. 1991, 113, 2761-2762.