Biological

Biological Chemistry seminar: Yi-Wei Chang, University of Pennsylvania

Thu, 2019-02-14 15:00 - 16:00
Speaker: 

Yi-Wei Chang

University of Pennsylvania

 

"Structural biology in situ by cellular electron cryotomography"


Electron cryotomography (ECT) enables intact cells to be visualized in 3D in an essentially native state to macromolecular (~4 nm) resolution. It has allowed us to visualize the structures of macromolecular machines in their native context inside intact cells. In many cases, such machines cannot be purified intact for in vitro study. In other cases, the function of a structure is lost outside the cell, so that the mechanism can be understood only by observation in situ. In this presentation, I will use bacterial secretion systems as examples to show how ECT can help us to understand important biological processes by doing structural biology directly inside cells.


Location: 

Carolyn Hoff Lynch Room

Cret, Chemistry Complex

Novartis Lectures (Julien Papillon, Novartis & Anna Pyle, Yale University)

Thu, 2018-11-29 14:00
Speaker: 

Dr. Julien Papillon

Novartis

 

Prof. Anna Pyle

Yale University

Location: 
Lynch Lecture Hall
Attached Document: 

Biological Chemistry seminar: Christina Woo, Harvard University

Thu, 2019-04-25 15:00 - 16:00
Location: 
Carolyn Hoff Lynch Room

Topic:  Small molecules and the proteome

Host:  Dr. David Christianson

Biological Chemistry seminar: Ned Wingreen, Princeton University

Thu, 2019-04-18 15:00 - 16:00
Location: 
Carolyn Hoff Lynch Room

Topic:  Intracellular networks

Biological Chemistry seminar, Susan Marqusee, University of California, Berkeley

Thu, 2019-04-11 15:00 - 16:00
Location: 
Carolyn Hoff Lynch Room

Topic:  Protein conformers

Host:  Dr. Feng Gai

Biological Chemistry seminar, Jake Jaffe, Broad Institute

Thu, 2019-03-28 15:00 - 16:00
Location: 
Carolyn Hoff Lynch Room

Topic:  Chromatin states

Host:  Dr. David Christianson

Biological Chemistry seminar: Thomas Pologruto

Thu, 2018-11-15 15:00 - 16:00
Location: 
Carolyn Hoff Lynch Room

"Introduction to Econophysics"

Biological Chemistry seminar: Andres Finzi, Université de Montreal

Thu, 2018-10-04 16:00 - 17:00
Location: 

Carolyn Hoff Lynch Room

Note 4:00 start time.

"Identification of a new HIV-1 Env conformation vulnerable to antibody attack"

Host: Dr. Amos Smith

Biological Chemistry seminar: Jason Beiger, Amgen

Thu, 2019-04-04 15:00
Location: 

Carolyn Hoff Lynch Room

Topic: Organic chemistry in biotechnology

Department of Chemistry

231 S. 34 Street, Philadelphia, PA 19104-6323

215.898.8317 voice | 215.573.2112 fax | web@chem.upenn.edu

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